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IK-175, an Oral AHR Inhibitor, as Monotherapy and in Combination with Nivolumab in Patients with Urothelial Carcinoma Resistant/Refractory to PD-1/L1 Inhibitors: Final Phase 1b Results

A First In Human Study of IK-595, an Oral MEK/RAF Molecular Glue, In Patients with RAS- or RAF- Altered Advanced Solid Tumors

IK-595, a best-in-class MEK-RAF molecular glue, drives broad and potent anti-tumor activity across RAS/MAPK pathway-altered cancers as a monotherapy and in combination

IK-595, a best-in-class MEK-RAF complex inhibitor, drives broad and potent anti-tumor activity in RAS/RAF-driven tumorsSource: From Ikena Oncology

IK-595 Targeting MEK-RAF Complex to Overcome CRAF Mediated Resistance & Drive Superior Anti-Tumor Activity in RAS/RAF Altered Cancers

IK-930, a Paralog Selective TEAD Inhibitor Effectively Attenuates Drug-Tolerant Persister Cell Proliferation

IK-930, a TEAD Paralog Selective Inhibitor for Treating YAP/TAZ-TEAD Dependent Cancers

IK-595, a MEK-RAF complex inhibitor, obviates CRAF mediated resistance resulting in superior RAS/MAPK pathway inhibition and anti-tumor activity in RAS/RAF altered cancers

IK-595, A MEK/RAF Complex Inhibitor, Obviates CRAF Mediated Resistance Resulting in Superior RAS/MAPK Pathway Inhibition and Anti-tumor Activity in RAS/RAF Altered Cancers

The Ah Receptor from Toxicity to Therapeutics. Report from the 5th AHR Meeting at Penn State University, USA, June 2022