The Ikena® Approach

We apply a translational lens to discover and develop novel cancer therapies across a wide range of mutations and patient populations.

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Ikena leverages a multifaceted approach to develop therapies that have potential as single agents and in combination to directly target the underlying mechanisms driving cancer survival and growth. Through a patient-centric, biomarker-driven strategy, we seek to expand the array of therapies that modulate key targets exploited by cancer.

Our Multifaceted Approach

Analyze cancer-driving targets in patients with significant therapeutic needs
We employ our insight and a wide array of technologies to identify genetic and signaling dependencies that enable cancer initiation, progression, metastasis, and therapeutic resistance. We are unconstrained to any single platform or method.
Identify patients that have specific cancer-driving targets
We leverage a diversity of translational approaches to identify patients that have cancer-driving mutations. We respond with flexibility and creativity to a growing body of data based on an array of biological markers, including creating novel assays as companions to our development candidates.
Employ tailored combination of capabilities to discover and develop therapies that target key drivers of cancer progression
Using a fit-for-purpose approach, we leverage our deep expertise in medicinal and computational chemistry and structural biology. With a platform-agnostic strategy, we let the biology determine the technologies we use to discover and develop clinical candidates.
Advance therapies that are guided by the patient–our North Star–from beginning to end
Our expertise, diverse processes, and dedication to evolving with science enable us to generate robust data and expand the toolbox of targeted therapies. Through this process, we are closer to achieving our mission of shifting the oncology treatment paradigm to a personalized, biology-driven approach for physicians and their patients.
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